About

Immunometabolism is a new and rapidly evolving field of research aiming to discover new mechanisms that control immune cell function.   Our studies focus on the metabolic regulation of T lymphocytes. These cells of the adaptive immune system play a central role in the immune defense against intruders, as well as maintaining tissue homeostasis and function. T lymphocytes respond to signals induced by infections and other threats to homeostasis. Cellular metabolic pathways act as intermediates between those signals and the outcome of T cell activation. Therefore, better understanding the role of metabolism in T cell function could lead to the development of novel therapeutic approaches to target dysregulated immune responses. This includes finding novel ways to suppress the uncontrolled immune response in proinflammatory diseases on the one hand and overcoming immune suppression in cancer patients or aged individuals on the other hand.